Level of Agreement and Correlation Between the Estimated Hemoglobin A1c Results Derived by Continuous or Conventional Glucose Monitoring Systems Compared with the Point-of-Care or Laboratory-Based Measurements: An Observational Study
Study brief:
In light of the current advances in diabetes management, the study aimed to investigate the level of agreement between the standard Lab-HbA1c with point-of-care testing (POCT-HbA1c) and glucose monitoring index (GMI) derived by intermittently scanned CGM (isCGM) or estimated average glucose (eAG) derived by conventional self-monitored blood glucose (SMBG) devices.
A cross-sectional study was performed on 81 diabetic patients at Diabetes Treatment Center, Prince Sultan Military Medical City, KSA, between May and December 2020.
Key findings:
Based on these results, the authors recommend using GMI derived by isCGM or eAG derived by conventional SMBG systems and the POCT-HbA1c measurements as potential methods for diabetes monitoring, especially when a rapid result is needed or with patients with uncontrolled diabetes or on intensive insulin therapy.
In light of the current advances in diabetes management, the study aimed to investigate the level of agreement between the standard Lab-HbA1c with point-of-care testing (POCT-HbA1c) and glucose monitoring index (GMI) derived by intermittently scanned CGM (isCGM) or estimated average glucose (eAG) derived by conventional self-monitored blood glucose (SMBG) devices.
A cross-sectional study was performed on 81 diabetic patients at Diabetes Treatment Center, Prince Sultan Military Medical City, KSA, between May and December 2020.
Key findings:
- HbA1c levels measured by POCT device showed a high level of agreement (>95%) with standard HbA1c laboratory test in both isCGM or conventional SMBG users
- The GMI measured by the isCGM showed a high level of agreement with HbA1c levels measured by the POCT device.
- The eAG measured by the conventional SMBG systems showed a high level of agreement with HbA1c levels measured by the POCT device.
- For uncontrolled DM patients, isCGM provides more personalized detailed glycemic data for a better diabetes care management plan.
- HbA1c levels measured by POCT device is a crucial method for diabetes screening and monitoring in daily clinic visits, especially when a rapid result is needed
Based on these results, the authors recommend using GMI derived by isCGM or eAG derived by conventional SMBG systems and the POCT-HbA1c measurements as potential methods for diabetes monitoring, especially when a rapid result is needed or with patients with uncontrolled diabetes or on intensive insulin therapy.